What Is BioGutPro?
BioGutPro is an innovative formulation that combines seven potent bioactive compounds to assist researchers who wish to study gut barrier function, regenerative processes, and localized inflammation:
BPC-157 (1000 mcg per serving *)
A synthetic peptide originally isolated from gastric juice, BPC-157 is currently being studied for its potential tissue-repair capabilities. Preclinical studies have shown it may:
- Accelerate intestinal and soft tissue healing by stimulating angiogenesis and fibroblast activity.
- Protect and repair the gut lining, possibly offering benefits for conditions associated with increased gut permeability.
- Reduce inflammation and oxidative stress, thereby supporting overall recovery and regeneration.
KPV (500 mcg per serving *)
This tripeptide (Lys-Pro-Val) is noted for its anti-inflammatory properties in animal models, potentially making it a key component in reducing gut inflammation:
- KPV modulates inflammatory cytokine activity and may ease gastrointestinal distress.
- KPV supports immune balance within gut tissue, which could help mitigate excessive pro-inflammatory cascades.
N-Acetyl Larazotide (500 mcg per serving *)
Designed to enhance intestinal barrier integrity, N-Acetyl Larazotide may help to regulate tight junction function in the gut epithelium via two mechanisms:
- Strengthening the intestinal lining to reduce permeability (useful for studying “leaky gut”).
- Promoting tight junction stability between gut epithelial cells, therefore limiting translocation of harmful agents.
GHK-CU (2 mg per serving *)
A well-researched copper-binding peptide that contributes to tissue regeneration and anti-inflammatory processes by:
- Stimulating collagen production and aiding in the repair of damaged tissues.
- Reducing local inflammation, possibly fostering a better biological healing environment.
CoreBiome® Tributyrin (400 mg per serving *)
A trademarked triglyceride form of butyric acid, CoreBiome® Tributyrin serves as a direct source of butyrate, an essential energy substrate for colonocytes:
- Provides nourishment to the gut lining, promoting mucosal integrity.
- Exerts anti-inflammatory effects to support a balanced gut microbiome.
Sodium Bicarbonate (150 mg per serving *)
A commonly used metabolic buffer that helps regulate gastrointestinal acidity in animal studies:
- Neutralizes excess stomach acid to create an optimal environment for gut function .
- Enhances nutrient absorption by maintaining a favorable pH balance within the gut.
Zinc L-Carnosine (100 mg per serving *)
This chelated compound pairs zinc with L-carnosine, a combination studied for its gut-supportive properties:
- Promotes the repair and maintenance of the stomach tissue and intestinal lining.
- Provides antioxidant and anti-inflammatory benefits to support mucosal defense.
* serving size = 2 capsules
Together, these components create a unique research model ideal for investigating gut healing, inflammation modulation, and mechanisms of tissue regeneration.
BioGutPro Research Compounds and Mechanisms
- BPC-157
Mechanisms:
- Enhances angiogenesis and fibroblast activation.
- Protects and repairs the gastrointestinal lining.
- Mitigates inflammation and oxidative damage.
- KPV
Mechanisms:
- Modulates cytokine responses to reduce inflammation.
- Supports balanced immune signaling within the gut.
- N-Acetyl Larazotide
Mechanisms:
- Enhances epithelial cell adhesion.
- Limits intestinal permeability to protect against external irritants.
- GHK-Cu
Mechanisms:
- Stimulates collagen synthesis and tissue remodeling.
- Facilitates anti-inflammatory and antioxidant activities.
- CoreBiome® Tributyrin
Mechanisms:
- Serves as an energy source for colonocytes.
- Modulates the inflammatory milieu in the gastrointestinal tract.
- Sodium Bicarbonate
Mechanisms:
- Buffers excess acidity to support mucosal health.
- Enhances nutrient assimilation and enzyme function.
- Zinc L-Carnosine
Mechanisms:
- Promotes mucosal repair and regeneration.
- Offers antioxidant and anti-inflammatory support.
Molecular Structure and Data
| Compound |
Molecular Formula |
CAS Number |
Molecular Weight |
| BPC-157 |
C₆₂H₉₈N₁₆O₂₂ |
137525-51-0 |
1419.54 g/mol |
| KPV (Lys-Pro-Val) |
C₁₆H₃₀N₄O₄ |
67727-97-3 |
342.43 g/mol |
| N-Acetyl Larazotide |
C₃₄H₅₉N₉O₁₂ |
881851-50-9 |
785.89 g/mol |
| GHK-Cu |
C₁₄H₂₀N₆O₄Cu |
18317-00-8 |
397.70 g/mol |
| CoreBiome® Tributyrin |
C₁₅H₂₆O₆ |
2802-18-6 |
302.40 g/mol |
| Sodium Bicarbonate |
NaHCO₃ |
144-55-8 |
84.01 g/mol |
| Zinc L-Carnosine |
C₉H₁₂N₄O₃Zn |
107667-60-7 |
289.61 g/mol |
Synergistic Mechanisms in BioGutPro
BioGutPro integrates these seven complementary bioactive compounds to create a research model for systemic gut healing:
- BPC-157 accelerates cellular repair and tissue regeneration.
- KPV minimizes inflammatory signals within the gastrointestinal tract.
- N-Acetyl Larazotide reinforces the gut barrier to prevent excessive permeability.
- GHK-CU enhances regenerative processes and mitigates inflammation.
- CoreBiome® Tributyrin nourishes colonocytes and supports mucosal integrity.
- Sodium Bicarbonate maintains optimal pH for enhanced nutrient uptake.
- Zinc L-Carnosine protects and repairs the gut lining while providing antioxidant benefits.
Together, these ingredients offer a comprehensive approach for investigating gut barrier restoration, inflammation modulation, and regenerative healing processes.
